Expression of SPANX proteins in human-ejaculated spermatozoa and sperm precursors
نویسندگان
چکیده
منابع مشابه
Apoptosis and necrosis in human ejaculated spermatozoa.
BACKGROUND Features of both apoptosis and necrosis have been reported in ejaculated human spermatozoa. This study examines the relative contribution of these two modes of cell death to the demise of these terminally differentiated cells. METHODS Sperm fractions were prepared from aliquots of semen samples from young normozoospermic donors by simple washing from seminal plasma, by discontinuou...
متن کاملOligozoospermia and heat-shock protein expression in ejaculated spermatozoa.
BACKGROUND Heat-shock protein A2 (HspA2) is correlated with sperm maturity, function and fertility, and a dysfunctional expression of such a gene results in abnormal spermatogenesis. The purpose of this study was to compare HspA2 gene expression in spermatozoa from oligozoospermic men and normozoospermic controls. METHODS Semen was obtained and analysed according to World Health Organization ...
متن کاملOrigin of DNA damage in ejaculated human spermatozoa.
The molecular basis of many forms of male infertility is poorly defined. One area of research that has been studied intensely is the integrity of the DNA in the nucleus of mature ejaculated spermatozoa. It has been shown that, in men with abnormal sperm parameters, the DNA is more likely to possess strand breaks. However, how and why this DNA damage originates in certain males and how it may in...
متن کاملThe expression and significance of CATSPER1 in human testis and ejaculated spermatozoa.
AIM To investigate the distribution of cation channel of sperm 1 (CATSPER1) protein and the presence of CATSPER1 mRNA in human testis and ejaculated spermatozoa. The influence of anti-human CATSPER1 antibody upon human sperm motility was used to evaluate the function of human CATSPER1 and to estimate its possible use as a target for immunocontraception. METHODS Human ejaculated sperm from nor...
متن کاملmiRNA-mediated regulation of heat shock proteins in human ejaculated spermatozoa.
BACKGROUND/AIM Heat shock proteins (HSPs) are expressed in human spermatozoa and play a role in sperm function. MicroRNAs (miRNAs) regulate gene expression, and the possible involvement of miRNAs in the regulation of HSP gene expression in sperm was investigated in this study. MATERIALS AND METHODS miRNAs differentially expressed in 8 copies of an oligoasthenozoospermic semen group (OA) were ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Andrology
سال: 2004
ISSN: 0105-6263,1365-2605
DOI: 10.1111/j.1365-2605.2004.00461.x